However, the vital question is Do they have the same effect
When people on TikTok say they're "microdosing" semaglutide at 0.25 mg per week, they are, in many cases, simply taking the FDA-approved starting dose of Ozempic
Researchers documented these milestones in uncovering the vision risks: Summer 2023: Three NAION cases presented at Mass Eye and Ear within a short period, all involving semaglutide users July 2024: Publication of the landmark Harvard study in JAMA Ophthalmology revealing increased NAION risk December 2024: Danish researchers published supporting studies involving over 424,000 patients 2025: Multiple international studies confirmed the association between semaglutide and vision problems The pivotal Harvard study analyzed medical records from 16,827 patients treated between 2017 and 2023, comparing those prescribed semaglutide against patients using other diabetes or weight loss medications
Many brands note on the can or bottle that their product isnt recommended for people under 18 (though CR testers say that in some cases, you have to look really closely to spot that information)
Different peptides work in unique ways