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One group developed Rapamycin-induced caspase 9 suicide gene, and co-expressed it with CD19 CAR to induce safety switch designed to selectively eliminate CD19 targeting CAR T cells in case of adverse effects (286)
Typical maintenance doses range from 0.5-1.0 mg per week , divided into smaller doses administered 2-3 times per week
Is it ironic that I, in fact, did make my sister buy (read: try) this class of medications
Long-term treatment may be necessary to maintain results, as stopping suddenly can lead to weight regain
Huyen VTT, Phan DV, Thang P, et al
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