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Insulin resistance: Paradoxically, while acute IGF-1 LR3 administration enhances insulin sensitivity, some research suggests chronic administration may produce compensatory insulin resistance over extended periods (12+ weeks)
However, another study by Cantini et al., used GLP-1(7-36), GLP-1(9-36) and Liraglutide to induce apoptosis in unstressed hASC, as assessed in annexin-V expression on the surface, though only the effect of Liraglutide and GLP-1(7-36) was partially reversed by the GLP-1-R-Antagonist Exendin(9-36), supporting receptor-specific activity [12]
They will then experience unwanted withdrawal symptoms when they try to quit
In these situations, the pharmacist can monitor the patient who is rapidly losing weight with an eye to closely watching weight-based chemotherapy dosing