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This function is mediated via the activation of the cAMP/PKA/CREB (cAMP-responsive element binding protein) and the transactivation of the EGF-R (epidermal growth factor receptor) leading to the activation of phosphatidylinositol-3 kinase (PI3K), protein kinase C(PKC), Akt-protein kinase B (AKT/PKB), extracellular regulated kinase (ERK1/2 or mitogen-activated protein kinase [MAPK]) signaling pathways and to the up-regulation of the expression of the cell cycle regulator cyclinD1 (Figure 3)
Food noise is different from normal hunger Food noise refers to persistent, intrusive, and often unwanted thoughts about food that can interfere with daily life
Yan H, Jia H, Wang X, Gao H, Guo X, Xu B
Mitonuclear protein imbalance as a conserved longevity mechanism
Medication adherence to injectable glucagon-like peptide-1 (GLP-1) receptor agonists dosed once weekly vs once daily in patients with type 2 diabetes: a meta-analysis
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