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For test compounds that were insoluble in water (Y1-R antagonists) stocks were made up at 1000 times the assay concentration in DMSO, so that final concentration of DMSO in the assay was 0.1%
The VEGFR2 pathway and nitric oxide synthesis via the Akt-eNOS axis promote angiogenesis, restoring blood supply to damaged nerve tissue
Frank J
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