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Learning from berberine: treating chronic diseases through multiple targets
GLP-1 albumin fusions stimulate insulin secretion through a GLP-1R-dependent mechanism To test the ability of the GLP-1 albumin fusions to activate the GLP-1R in vitro, we used a human GLP-1R reporter cell assay kit, where serial dilutions of unfused GLP-1, GLP-1 WT, or GLP-1 QMP were incubated with the cells overnight (Fig
It acts as a receptor agonist, which means it plugs into receptors in the body that respond to the GLP-1 hormone
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