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To investigate how metformin exerted its antioxidant effects, we first examined the expression of Nrf2 and its downstream regulatory protein HO-1 in the chondrocytes exposed to H 2 O 2 , with or without metformin treatment

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Estradiol increases body weight loss and gut-peptide satiation after roux-en-Y gastric bypass in ovariectomized rats

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A large retrospective cohort study involving 283,004 matched pairs found that tirzepatide users actually had a 65% lower incidence of malignant thyroid cancer compared to non-users, with a relative risk of 0.348