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Research-context answer No human study has compared the two
This is because many people cant absorb enough B12 from food
Evidence behind common 5-Amino-1MQ benefit claims Claimed outcome Fat-mass changes Evidence level Animal evidence What research currently shows Obese mouse studies reported less body-weight gain, lower fat mass, or smaller fat cells after NNMT inhibition
It promotes lipolysis through growth hormone receptor pathways, which differs from the NNMT inhibition mechanism of 5-amino-1mq
Source: Awosemo et al., Journal of Pharmaceutical and Biomedical Analysis, 2021
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