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The vitamin can be stored in the liver for a long time, so it may take a few years for a deficiency to develop

Since vitamin B12 is water-soluble, your body typically just flushes out any extra it doesn't need

Mass spectrometry can support identity confirmation, but a matching mass alone does not characterize sequence-related impurities, positional isomers, disulfide variants, aggregates, residual reagents, or all degradation products

22 The causes of aphthous ulcers are unknown, and may include systemic diseases, nutritional deficiencies, food allergies, genetic predisposition, immune disorders, medications and human immunodeficiency virus infection

This stability extends to reconstituted solutions, which can maintain potency for several weeks when properly refrigerated