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In support, preclinical studies have indicated reduced efficacy of HCC immunotherapies in NASH-HCC mouse models compared to non-NASH HCC mouse models 12,14,15 , inviting the possibility that NASH may be an immunologically distinct pro-tumorigenic liver disease
The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review
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