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Mendez-Lucas, A

Human Clinical Data (20242025): While much of the early data was preclinical, a 2025 systematic review in HSS Journal analyzed its emerging use in sports medicine

For example, while Lactobacillus kefiranofaciens is dominant at the beginning of fermentation , Leuconostoc mesenteroides may dominate at the end (111)

It can also help aid skin burns to heal at a faster rate and increase blood flow to damaged tissues

When the gut lining is inflamed and permeable, neurotransmitter production is disrupted, inflammatory cytokines cross into systemic circulation and reach the brain, and the vagus nerve the primary communication cable between gut and brain transmits distress signals that manifest as anxiety, brain fog, and fatigue