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MOTS-c is a prescription peptide

The upregulation of type A monoamine oxidase (MAOA) and the downregulation of serotonin (5-hydroxytryptamine, 5-HT) and NE levels in the brain are considered to be the primary etiological factors underlying depression

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However, it declines with age

10.1038/nature20132 136 LabuschagneC