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harmful microorganisms
Data acquisition was using an Agilent 6546 Q-TOF instrument (ESI) with optimized parameters: gas temp 300 C, drying/sheath gas 8/11 L/min, capillary voltage 3500 V, and spray voltages 500/1000 V
GSH is known to cleave disulfide and diselenide bonds by binding to one cleaved thiol/selenol, forming another disulfide or sulfide-selenide linkage, liberating the other half of disulfide/diselenide as a thiol/selenol, thus being an efficient reducing agent
DADS and DATS inhibited the expression of adhesion molecules, E-selectin and vascular cell adhesion molecule-1 (VCAM-1), on endothelial cell surface by reversing oxidized LDL-induced inhibition of PI3K/Akt and cAMP responsive element binding protein (CREB) signaling pathways (50)
Trepanowski JF and Bloomer RJ
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