weight loss on glp-1 Half of users ditch their injections — and some are turning to other weight-loss methods instead Part 1 of a 3-Part

Newer oral GLP-1 options like the Wegovy pill are more affordable currently around $149 per month but clinical trials show they deliver somewhat less weight loss than injectables, averaging around 1516% compared to 20% or more with injections. For patients who need significant weight loss to resolve health conditions, a lower-cost medication that produces fewer results may not be enough

Amplifying GH release beyond physiological ranges carries its own concerns, discussed in the safety section below

However, for the about 30% of adults who have trypanophobia or a fear of injections the need to self-inject these medications may keep them from using them

But its also possible that GLP-1 drugs have a direct therapeutic effect (for example, by reducing inflammation) that works independently of weight loss

DOI: 10.1080/14656566.2024.2343092