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The only difference between them: Mounjaro - Approved for type 2 diabetes (and used off-label for weight loss) Zepbound - Approved specifically for chronic weight management Same molecule, same injection sites, same technique, same considerations about site rotation
Rush EC, Patel M, Plank LD, Ferguson LR
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Duration of treatment also mattered: people who took tirzepatide for longer periods showed somewhat better metabolic adaptation, though regain still occurred after discontinuation
Another analysis found that creatine supplementation can blunt lean mass decline by up to 60% compared to non-supplemented controls in hypocaloric states
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