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The FDA-mandated Boxed Warning for Zepbound states that tirzepatide causes thyroid C-cell tumors in rodents and that it is unknown whether Zepbound causes thyroid C-cell tumors, including MTC, in humans
Mechanisms not driven by glycaemic control alone To explore potential mechanisms, the researchers conducted mediation analyses
In the phase 3 SELECT trial of Wegovy, the drug lowered major adverse cardiovascular events (MACEs) by 20%
Tirzepatide (weekly) is a dual GIP/GLP-1 agonist with potentially greater results
In a statement to Fortune last month, Novo Nordisk said there was no mistake regarding its patent maintenance fee in Canada and declined to comment on other drug manufacturers plans
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