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The demographic of people aged 80 years and above is growing at a faster rate
The compounded medication itself is not FDA-approved
N Engl J Med 373:21172128 Neal B, Perkovic V, Mahaffey KW, de Zeeuw D, Fulcher G, Erondu N, Shaw W, Law G, Desai M, Matthews DR (2017) Canagliflozin and cardiovascular and renal events in type 2 diabetes
These findings suggest that GIP but not GLP-1RA may improve glucose disposal by ameliorating peripheral insulin sensibility and glucose utilization, while GIP added on to GLP-1RA may reduce food intake with a combined effect resulting in improvement of glucose control and weight loss
Common issues include increased heart rate, elevated blood pressure, and insomnia
