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[0016] In some particular embodiments of the present invention, the coupling in step 2 of the preparation method is performed by condensing with DIC+A or B+A+C until the resin is detected to be transparent with ninhydrin, wherein A is chosen from HOBt or HOAt, B is chosen from HBTU, HATU, TBTU, PyAOP, or PyBOP, C is chosen from DIPEA or TMP
Always follow the guidance of your healthcare provider and report any issues or concerns to them promptly
Mendelian randomisation in cardiovascular research: an introduction for clinicians
doi:10.1016/B978-0-12-800892-8.00003-8