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Rico et al
Because semaglutide does not rely on these pathways, it has a relatively low potential for direct pharmacokinetic drug interactions with most commonly prescribed medications, as confirmed in the European Medicines Agency's European Public Assessment Report (EPAR)
For example, a meta-analysis of 31 randomized, controlled trials reports that the most common side effects observed in the hGH studies and their respective incidences were [16]: Soft tissue edema: 50% Insulin resistance: 22% Arthralgias: 21% Carpal tunnel syndrome: 19% These side effects are transient and usually subside as the patient gets used to the therapy
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Yes, nausea is a common side effect of semaglutide, especially at higher doses
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