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125127 When pyruvate kinase is deficient or dysfunctional, there is an increased reliance on alternative pathways for energy production leading to increased breakdown of ATP and subsequent accumulation of adenosine monophosphate

Once released, GH stimulates the liver to produce insulin-like growth factor-1 (IGF-1), which plays a crucial role in the body's anabolic processes

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In: Ocular Disease Mechanisms and Management, 2010:238-242

& Pinnen, F