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Remarkably, despite having minimal effects on the expression of hepatic markers of inflammation in one of these two studies (86), its administration significantly decreased the gene expression of chemoattractants for different immune cells in the liver of treated mice (interferon -induced protein 10, i.e., CXCL10, and RANTES, i.e., CCL5), which are commonly dysregulated in liver fibrosis (108)

The Shield Against Damage Making thyroid hormones produces hydrogen peroxide as a by-product

5 min prior to anesthesia, all mice received 0.1 g/g body weight buprenorphine-HCl intraperitoneally for analgesia

These findings indicated that high glucose induces PSC activation via the TGF signalling pathway

DaviesMJD'AlessioDAFradkinJKernanWNMathieuCMingroneGet al