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Summary of Product Characteristics, Wegovy (semaglutide) injection
One case series (Fiaova et al., Endocrine Practice , 2024) reported 8 unplanned pregnancies in 340 women treated with GLP-1 agonists for weight loss, all in women with prior PCOS diagnoses who believed they had low fertility
In clinical trials, severe GI adverse reactions were reported more frequently among patients who received Ozempic injection (0.5 mg 0.4%, 1 mg 0.8%) than placebo (0%)
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