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Whether this translates to human risk is not established, but the medication is contraindicated in anyone with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

The drug met its primary statistical endpoint, showing significant and superior improvements in HbA1c for all three doses compared to placebo

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This can result in increased shedding and noticeable hair thinning, typically appearing a few months after rapid weight loss begins and may be more pronounced in women and older adults

Garza et al