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Scott Butsch, director of obesity medicine at Cleveland Clinics Bariatric and Metabolic Institute
Be wary of "research peptides," unlabelled vials, or anything sourced online
The pharmacokinetics of LY3437943 (retatrutide) support once-weekly administration due to an elimination half-life of approximately 6 days. Jastreboff AM et al., Nature Medicine, 2023 This extended half-life is made possible by attaching a fatty acid chain to the peptide, allowing it to bind to albumin a common protein in your blood that acts like a slow-release carrier
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However, since a single area could mean the removal of varying amounts of fat, the amount of time required will be different too
