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Description

When increased urination occurs, it typically reflects indirect factors such as improved blood glucose control, dietary changes, increased fluid intake, or co-prescribed medications like SGLT2 inhibitors or diuretics

and effects of BCAA metabolites such as 3-HIB on vascular lipid transport (91)

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Taken together, evidence from neuroscience, human research, and clinical practice suggests meaningful overlap between obesity and addiction-related mechanisms. Lorenzo Leggio, MD, PhD, clinical director, National Institute on Drug Abuse, Bethesda, Md