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Following H 2 O 2 treatment for 24 h, primary ectopic ESCs exhibited increased ROS levels and MDA expression, along with decreased levels of peroxidase enzymes (superoxide dismutase, total glutathione peroxidase, and catalase) due to consumption (Supplementary Fig
Depending on the needs of the study, prepared solutions may be maintained under refrigerated conditions for short-term use or frozen for longer-term laboratory storage, with aliquoting commonly used to help maintain sample integrity during repeated use
At the molecular level, astaxanthin upregulates synaptic proteins involved in both pre- and postsynaptic function, such as synaptophysin, PSD-95, and SNAP-25, while promoting neurotrophic signaling through the BDNF/TrkBCREB pathway
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