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A heart disease study of semaglutide in patients with type 2 diabetes (SOUL) Accessed 22 Mar 2021

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(And while slightly increasing GLP-1 levels wont result in extreme weight loss, you certainly dont want to cause them to nosedive, either.) A 2023 study found that folks with a misaligned circadian rhythm (due to factors like night shift work or insomnia) tend to have a low GLP-1 response and a high risk of insulin resistance and obesity (18)

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When Mounjaro suppresses our appetite and reduces caloric intake, this heat-generating effect may decrease, potentially leading us to feel colder than usual, particularly between meals

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