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The process according to claim 1, wherein fragment A is selected from the group consisting of His-Xi-Glu-Gly-Thr-Phe-Thr-Ser(\|/ z ' z pro) His-Xi-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser(\|/ z ' z pro) His-Xi-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser(\|/ z ' z pro) His-Xi-Glu-Gly-Thr-Phe-Thr(\|/ z ' z pro) and His-Xi-Glu-Gly-Thr(\|/ z ' z pro) wherein Xi is Ala or Aib, and wherein (y z ' z rto) indicates that Ser, or Thr, is pseudoproline protected, according to the formula : Y is hydrogen for Ser and Me for Thr, Z is hydrogen or Me, and Ri is the side-chain of the amino acid beside the pseudoproline protected amino acid

The need for treating obesity as a chronic condition is highlighted by the fact that weight regain happens after stopping semaglutide, despite lifestyle modifications [116]

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With the right plan, continued lifestyle support, and healthcare supervision, you can transition safely and maintain long-term success