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When you then switch to tirzepatide, you are now stimulating both GLP-1 and GIP receptors
You will continue to come in-office for your weekly injections
Perhaps more importantly for tolerability, GIP activation seems to buffer against the nausea commonly caused by GLP-1 stimulation alone
Kahles F, Liberman A, Halim C, et al
Despite both culminating in GH release, the receptor systems, signaling cascades, and structural requirements differ substantially [1][2]
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