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The expression of NRF1 is highest in skeletal muscle which is also the tissue that accounts for the largest percentage of glucose disposal in the body and, therefore, is the tissue that is most responsible for the hyperglycemia resulting from impaired insulin signaling
Machine learning-assisted metabolomics analysis provides new possibilities for this endeavor (152)
Activated RAC1 binds to the C-terminus of NOX1, activating NOX1 and inducing ROS production, which is prone to forming a vicious cycle (Liu-Smith et al., 2014)
Glutathione S-transferase T1 (GSTT1) null polymorphism, smoking, and their interaction in coronary heart disease: a comprehensive meta-analysis
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