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This N-terminal domain of GSDMD can be transported to the cell membrane, assembling into pore structures that release IL-1 and IL-18, leading to excessive inflammation and cell death
doi: 10.1093/eurheartj/ehz231 146 WangZRobertsABBuffaJALevisonBSZhuWOrgEet al
What they found: In the control group 70 % of rats died within 30 days In the BPC-157 group only 10 % died Histology: faster formation of collaterals, normalization of portal vein pressure, 80 % reduction in liver thromboses Why it matters: These are extreme conditions
Contact our peptide specialists: References Maquart, F
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