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Reducing Oxidative Stress In The Brain Glutathione directly neutralizes ROS and peroxides

However, human data confirming this across all dose ranges is limited

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Together, excessive and reduced production of neuro-toxic and -protective kynurenines, respectively, may exacerbate excitotoxicity and neuroinflammation, establishing a feed-forward cycle of KP dysregulation, 5-HT depletion, HPA axis hyperactivity, and increased vulnerability to MDD

Studies havent been able to prove whether B12 can improve or reverse memory loss once it becomes problematic