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UK product information for GLP-1 receptor agonists contains special warnings and precautions regarding thyroid C-cell tumours (medullary thyroid carcinoma) based on rodent studies
A related line of evidence involves sodium-glucose cotransporter 2 inhibitors (SGLT-2i)
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Because it works through the natural GHRH pathway, adverse effects tend to be mild and self-limiting
Several studies report alterations in peripheral plasma concentrations of GSH and GSH related enzymes, however research suggests central GSH dysfunction differs from peripheral dysfunction (62)
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