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However, some individuals may experience persistent nausea or develop constipation as gastric emptying remains slowed
243 Mito-nuclear communication also plays a role in LHON pathogenesis, as evidenced by the activation of mt-ISR transcripts in LHON, which leads to chronic inhibition of protein synthesis, affecting synaptic and oligodendroglial function, and contributing to disease progression
Peer-reviewed studies have reported GHK-Cu's involvement in collagen synthesis, extracellular matrix remodeling, wound repair acceleration, hair follicle activity, and broad gene expression modulation
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