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Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation
Oliveira N
10.3390/ijms25147603 34
Satiety per se limits the duration of the meal or the "meal size"
Reordered clinics with Eden moved above Shed
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