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When the sensitivity of ELF was independently varied from 0 to 100%, ELF/TE was the most cost-effective strategy when ELF sensitivity exceeded 71.5%

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If a 3% reduction in baseline body weight is not observed after 12 weeks, the dosage can be escalated to 11.25/69 mg for an additional 14 days and subsequently increased to 15/92 mg daily

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