Liraglutide (the active ingredient in Saxenda and Victoza) and semaglutide (the active ingredient in Ozempic) are two of the most studied options, and while they work through the same pathway, they differ in dosing, potency, side effects, and the kind of support they offer over time
Increasingly, Afshar is initiating conversations with patients who he says are "not that overweight" but who he thinks could use these drugs to boost their longevity by driving down visceral fat stores and lowering inflammation across the body
This leads to reduced appetite, feeling full more quickly and slowed stomach emptying
Wegovys demand has crept into increased off-label prescriptions of Ozempic, reducing access for patients with diabetes9
Clinical Efficacy In a two-year trial, participants receiving semaglutide experienced a mean weight loss of 15.2% from baseline, with over 75% losing 5% of their initial weight