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The dual GIP/GLP-1 mechanism means degradation affects two receptor pathways rather than one

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In this case, medications approved to treat type 2 diabetes may have been used off-label for obesity management because there was a shortage of those that were approved for weight loss, such as Wegovy

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After sema treatment, no apparent improvement in liver stiffness was observed, but fewer subjects had substantial increases in this marker of fibrosis.

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