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The modest increase in heart rate associated with semaglutide may be a consideration in patients with compromised cardiac function
Clinical trials and studies have reported various cardiovascular events among users
Notably, GLP-1 receptors are expressed on EAT adipocytes, and their levels correlate with the expression of genes regulating fatty acid metabolism, adipogenesis, brown fat activation, and white-to-brown fat differentiation [112]
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Romero-Gomez M, Lawitz E, Shankar RR, Chaudhri E, Liu J, Lam RL, et al
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