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Because both drugs work in a similar way, they share most of the same side effects
1,2 Investigators of the study found that semaglutide significantly reduced the risk of major adverse cardiovascular events (MACE) such as CVD death, heart attack, and stroke, which occurred in 6.5% of individuals in the semaglutide group compared with 8% of those in the placebo group
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Regardless of the name, GLP-1s imitate natural hormones in the body and impact several metabolic functions
The SURMOUNT-1 trial showed that patients regain approximately 50% of lost weight within 12 months of discontinuing tirzepatide (Jastreboff et al., NEJM , 2022)
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