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In summary, eight methylation biomarkers for CC screening and early detection are described, while the others are listed in Table 4
The product also downregulates lipogenic genes (e.g., FAS, SREBP1c), further improving hepatic lipid metabolism-again via nicotinamide regulation and NAD+ homeostasis
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Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease
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