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One animal study (Valdecantos et al., ADA 2024) showed obese rats given both compounds at sub-maximal doses lost more weight than either compound alone
The expression of interleukin-1 (IL-1) and interleukin-6 (IL-6) in the plasma was detected using an enzyme-linked immunosorbent assay (ELISA) kit (Servicebio, China) following the manufacturers instructions
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While the injection itself is quick, the process around it matters
Sigma Aldrich, Milwaukee, WI), a laparotomy was performed, and both renal pedicles were clamped for 22 min
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