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It was noted that IGF-1 LR3 might potentially be 1.5 to 2 times as anabolic as IGF-I in inducing weight gain, increasing visceral organ weights, and possibly enhancing feed use efficiency under continuous delivery conditions
However, because Wegovy reaches higher doses (up to 2.4 mg), absorption consistency becomes even more critical for managing appetite
Gradual dose titration, smaller meals, avoiding high-fat foods, and staying upright after eating can reduce nausea and vomiting
Extended time outside refrigeration degrades the peptide structure
PMID 11821065
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