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One of these medications is liraglutide

Last updated June 3, 2026 Editorial policy The Dual Effect No One Expected When patients started reporting that their GLP-1 medications were curbing both their appetite and their desire to drink, clinicians paid attention

102,189,320,330 In patients with lower eGFR levels, uricosuric agents may not be as effective, necessitating the use of alternative agents with different mechanisms of action

Inhibition of the myostatin-Smad2/3 signaling pathway not only alleviates inhibition of the IGF-1-PI3K-Akt-mTOR signaling pathway but also downregulates MAFbx expression (140,141)

To learn more about how Trulicity is used, see the What is Trulicity used for? section