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[PMID: 41346202] Laboratory literature summary: What effect does semaglutide have on those living with metabolic research models
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Authors' contributions YW wrote the manuscript, conceived the topic of review and collected the data
The direct delivery of substances via IV therapy allows for higher concentrations to be achieved in the bloodstream than might be possible through oral ingestion
Henney et al
For instance, the pleckstrin homology domain interacting protein (PHIP) protein acts as a transcriptional co-regulator that directly modulates POMC transcription, whereas the SIM1 transcription factor is indispensable for the normal development of the PVN and the proper expression of MC4R [8,13]
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