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As a fatty acid amide, PEA interacts with the peroxisome proliferator-activated receptor alpha (PPAR-$\alpha$) and G-protein coupled receptors to down-regulate mast cell activation, offering an advanced model for studying the mitigation of visceral pain and chronic neuro-inflammatory signaling along the enteric nervous system
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Lower purity samples may contain impurities that alter study results
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JAMA 1998;279:1962-7
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Research chemical suppliers are not subject to pharmaceutical manufacturing standards, and contamination or mislabeling is a documented risk
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Halsted, J
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