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One of these Nrf2 targets, haem oxygenase-1 (HO-1), has two purposes in ferroptosis: promotion of ferroptosis via the generation of Fe 2+ from haem degradation, and deceleration of ferroptosis through the inhibition of oxidative stress
PMID: 41965309 Chen S et al
In fibroblast-like RA synoviocytes, the administration of lixisenatide resulted in a reduction in the inflammatory response
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