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doi: 10.1111/pde.15106, 35

For instance, in NSCLC cells, elevated lactylation of histone H3 reduces glycolysis and maintains mitochondrial balance by altering mRNA levels of glycolytic enzymes ( HK1, PKM ) and TCA cycle enzymes ( SDHA, IDH3G ), highlighting the crosstalk between histone Kla and glucose metabolism in cancer progression

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