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Wilkerson EC, Goldberg DJ
The tirzepatide to semaglutide switch requires careful dose conversion since the medications are not equivalent milligram for milligram
For anyone whose levels have dropped critically low, an IV infusion delivers the rapid correction that a standard intramuscular shot simply cannot match
Discontinuation of GLP1RAs and tirzepatide can also result in a loss of the beneficial anti-atherosclerotic and plaque-stabilizing effects of these medications
First, it can impair the transport of long-chain fatty acids into the mitochondrial matrix, with subsequent decrease in -oxidation, acetyl-CoA and ATP production
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