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In addition, several molecules have been studied as an adjuvant therapy, including L-carnitine, CoQ 10 , vitamin E, vine tea polyphenol, cytoprotective agents (ursodeoxycholic acid), and insulin sensitizers (pioglitazone and metformin) (94)
Lead author Professor John Deanfield (UCL Institute of Cardiovascular Science) said: Our previous SELECT analysis showed the benefits of semaglutide for people with cardiovascular disease who had obesity or were overweight
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Furthermore, we should be aware that when applying semaglutide in older individuals with long-term diabetes, in addition to causing gastrointestinal adverse reactions (mild or moderate nausea, vomiting, constipation, diarrhea), it may also increase the risk of diabetic retinopathy complications, which is still a matter of debate [10]
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